JASCO SCF-VCH-BP Valve Change Units SCF-VCH-BP TAB22A-4/PURF2-LF W/ 2L81-000001-14 2L81-050039-41 396uW 4022.454.71615 5517D-C19 6

Technical Dossier

Product Details And Specifications

JASCO SCF-VCH-BP Series: Comprehensive Valve Change Unit Range and Technical Overview

The JASCO SCF-VCH-BP series is a line of valve change units engineered specifically for use within JASCO's Supercritical Fluid Chromatography (SFC) and Supercritical Fluid Extraction (SFE) instrument platforms. These units are deployed in analytical and preparative SFC systems across pharmaceutical manufacturing, petrochemical refining, food safety laboratories, and environmental testing facilities. The SCF-VCH-BP designation identifies back-pressure-regulated valve change assemblies that manage mobile phase switching, column selection, and flow path diversion within high-pressure CO₂-based chromatographic systems. JASCO SFC platforms are installed in regulated GMP environments globally, making reliable spare part availability a critical operational requirement.

The Evolution of SCF-VCH-BP Architecture

JASCO introduced its modular SFC platform in the early 2000s, with the SCF series establishing a standardized instrument bus for chromatography system components. Early valve change units in this lineage used discrete solenoid-actuated switching valves with manual back-pressure regulators. As SFC adoption expanded into preparative-scale pharmaceutical purification, JASCO redesigned the valve change architecture to incorporate integrated back-pressure regulation (the -BP suffix), enabling automated pressure control across multiple flow paths without external regulators.

The TAB22A-4 valve body designation indicates a 4-port, 2-position switching configuration rated for high-pressure CO₂ service. The PURF2-LF suffix identifies a low-flow purge function variant, suited for analytical-scale column switching. Component sub-assemblies such as the 2L81-000001-14 and 2L81-050039-41 are internal valve actuator and seal kit references used in JASCO's service documentation. The 396uW power specification and 4022.454.71615 part number cross-reference to JASCO's internal BOM system. The 5517D-C19 designates the controller interface board revision, and the trailing 6 indicates the valve port count variant.

Compatibility across SCF-VCH-BP generations is constrained by the instrument bus revision and the back-pressure controller firmware version. Units from pre-2010 platforms are not directly interchangeable with post-2015 SFC-4000 series instruments without firmware and connector adaptation.

SCF-VCH-BP Full Catalog & Functionalities (SKU List)

Valve Change Units & Flow Path Assemblies

• SCF-VCH-BP TAB22A-4/PURF2-LF: 4-port/2-pos back-pressure valve change unit, low-flow purge, analytical SFC.
• SCF-VCH-BP TAB22A-6/PURF2-LF: 6-port/2-pos back-pressure valve change unit, low-flow purge variant.
• SCF-VCH-BP TAB22A-4/PURF2-HF: 4-port/2-pos back-pressure valve change unit, high-flow purge, preparative SFC.
• SCF-VCH-BP TAB26A-6/PURF2-LF: 6-port/2-pos high-pressure valve change unit, analytical column switching.
• SCF-VCH-BP TAB26A-4/PURF2-HF: 4-port/2-pos high-pressure valve, preparative-scale flow path control.
• SCF-VCH TAB22A-4/PURF2-LF: Standard (non-BP) 4-port valve change unit, manual back-pressure regulation.
• SCF-VCH TAB22A-6/PURF2-LF: Standard 6-port valve change unit for multi-column SFC configurations.

Internal Sub-Assembly & Actuator Components

• 2L81-000001-14: Valve actuator assembly, solenoid-driven, for SCF-VCH-BP TAB22A series.
• 2L81-050039-41: Seal and rotor kit for TAB22A-4 valve body, CO₂-compatible PEEK/PTFE.
• 2L81-000001-12: Valve actuator assembly, earlier revision, TAB22A pre-2012 units.
• 2L81-050039-38: Seal kit, earlier revision, for TAB22A-4 pre-2012 valve bodies.
• 2L81-050039-45: Seal kit, high-pressure variant, for TAB26A series valve bodies.

Controller Interface & Electronics

• 5517D-C19: Controller interface board, revision 19, for SCF-VCH-BP instrument bus integration.
• 5517D-C17: Controller interface board, revision 17, compatible with SCF-4000 series pre-2018.
• 5517D-C15: Controller interface board, revision 15, legacy SCF-2000 series compatibility.
• 4022.454.71615: JASCO BOM cross-reference part number for SCF-VCH-BP TAB22A-4 complete assembly.

Back-Pressure Regulation & Power Components

• SCF-BPR-2080: Automated back-pressure regulator module, pairs with SCF-VCH-BP series.
• SCF-BPR-2080/HT: High-temperature back-pressure regulator, for elevated-temperature SFC methods.
• 396uW Power Module: Internal power supply reference (396 microwatt rated), valve solenoid drive circuit.

Quality Control for the SCF-VCH-BP Range

SCF-VCH-BP valve change units present specific inspection requirements due to their high-pressure CO₂ service environment and precision rotor-stator sealing surfaces. DriveKNMS applies the following test protocol to all SCF-VCH-BP units prior to dispatch:

• Pressure integrity test: Each valve body is pressure-tested at 1.5× rated operating pressure using inert gas (N₂) to verify seal integrity across all ports.
• Rotor-stator surface inspection: Optical inspection of PEEK/PTFE rotor and stator contact surfaces for scoring, delamination, or chemical degradation from CO₂/modifier exposure.
• Solenoid actuator function test: Electrical actuation cycling (minimum 50 cycles) to confirm solenoid response time and valve switching repeatability.
• Controller interface board verification: Bench-level continuity and signal integrity test on the 5517D-C19 interface board, including instrument bus communication handshake simulation.
• Leak-down test: Static pressure hold test (30 minutes minimum) to confirm zero pressure decay across valve body seals.
• Dimensional verification: Port geometry and fitting thread verification against JASCO engineering drawings to confirm cross-compatibility with target instrument platform.